Monday 21 March 2011

kawasaki disease

Kawasaki's Disease History:
Kawasaki syndrome (KS), also known as Kawasaki disease, an acute febrile disease of unknown etiology affecting primarily children under the age of 5 years of age. It was first described in Japan Kansas Tomisaku Kawasaki in 1967, reported the first cases outside of Japan in Hawaii in 1976.
Kansas occurs in all parts of the world, the highest rate in Japan, and most often affects children and young children. Kansas may be seasonal in winter, spring, have been reported outbreaks of community-wide, in some cases. In the continental United States, and estimated the population-based studies and hospital occurrence of KS ranging from 9 to 19 per 100,000 children aged under 5 years of age. Estimated about 4248 in hospitals with Kansas, of which 3277 (77%) of children under the age of 5 years of age, and among children under the age of 18 years of age in the United States in 2000. In 2006, the total number of hospitals with Kansas 5523 (standard error [South East] 289) and the percentage of children under the age of 5 years of age remained the same.

Cases that go untreated can lead to more serious complications, such as vasculitis, inflammation of the blood vessels. This can be particularly dangerous because it can affect the coronary arteries, which supply blood to the heart.

In addition to the coronary arteries, heart muscle, lining, valves, and the outer membrane that surrounds that can become inflamed heart. Arrhythmias (changes in the normal pattern of the heartbeat) or abnormal functioning of some heart valves can also occur.
Diagnosis

Can not test one for detection Kawasaki disease, so doctors usually diagnosed by evaluating symptoms and the exclusion of other conditions.

Most children diagnosed with Kawasaki disease will have a fever lasting 5 days or more and no less than four of these symptoms:

     Redness in both eyes
     Changes around the lips, tongue, or mouth
     Changes in the fingers of the hands and feet, such as swelling, discoloration, or peeling
     Rash on the trunk or genital
     Large lymph node in the neck
     Red, swollen palms of the hands and soles of the feet

Rocky Mountain spotted fever if there is doubt, Kawasaki disease, the doctor may order tests to monitor heart function (such as the echocardiogram) and might take blood and urine samples to rule out other conditions, such as scarlet fever, measles, fever, juvenile rheumatoid arthritis, or allergic reaction drug .
Treatment

Should begin treatment as soon as possible, ideally within 10 days of the fever when it starts. Usually, the child is treated with doses of intravenous gamma globulin (purified antibodies), component of blood that help the body fight infection. The child and can also be given a high dose of aspirin to reduce the risk of heart disease.

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